Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI3A4), TrueMAB

Applications and Tested Dilution

Product Specifications

Target Information

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It functions as a homodimer and plays a critical role in glycolipid breakdown. The NAGA gene encodes a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates and maps to human chromosome 22q13.2.

Defects in NAGA cause autosomal recessive disorders known as Schindler disease (types I, II, and III) or NAGA deficiency, characterized by varying degrees of neurologic manifestations.

• Type I: Most severe form
• Type II (Kanzaki disease): Mild intellectual impairment, angiokeratoma corporis diffusum
• Type III: Mild-to-moderate effects

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.