Thermo Fisher Scientific iNOS Polyclonal Antibody, Biotin
Thermo Fisher Scientific의 iNOS Polyclonal Antibody, Biotin은 인간, 마우스, 랫트 반응성을 가지며 Western blot, ELISA, IP에 사용 가능. Biotin 결합형으로 고순도 Affinity chromatography 정제. 세포 내 iNOS 단백질 검출 및 NO 신호 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–150 of human inducible nitric oxide synthase (iNOS) protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Inducible nitric oxide synthase (iNOS) produces nitric oxide (NO), a gaseous free radical involved in vasorelaxation, neurotransmission, and cytotoxicity. NO is synthesized from L-arginine by NOS enzymes. iNOS expression is inducible by lipopolysaccharide and cytokines such as IFN-γ, TNF, and IL-1/2. It is found in macrophages, hepatocytes, synoviocytes, and smooth muscle cells. iNOS activity increases after cytokine stimulation, leading to prolonged NO production. Dysregulation of iNOS is linked to diseases like achalasia and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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