Thermo Fisher Scientific iNOS Polyclonal Antibody, FITC
FITC로 표지된 Thermo Fisher Scientific iNOS 폴리클로날 항체로, 인간 iNOS 단백질(1064-1114 aa)에 특이적입니다. Western blot, ELISA, IP 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. -20°C 암소 보관.
- 카탈로그번호
- INOS-112-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific iNOS Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1064–1114 on human inducible nitric oxide synthase protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
iNOS (Inducible Nitric Oxide Synthase, NOS) is an enzyme responsible for producing nitric oxide (NO), a gaseous free radical involved in vasorelaxation, neurotransmission, and cytotoxic responses.
iNOS is expressed in the liver and induced by lipopolysaccharides and cytokines such as IFN-γ, TNF, and IL-1/2. It catalyzes the oxidation of L-arginine to L-citrulline and NO.
Three NOS isoforms are known: neuronal (nNOS, type I), endothelial (eNOS, type III), and inducible (iNOS, type II).
iNOS is found in macrophages, hepatocytes, synoviocytes, and smooth muscle cells.
Dysfunction in iNOS is associated with diseases such as achalasia and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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