Thermo Fisher Scientific SOX10 Recombinant Rabbit Monoclonal Antibody (PDH0-04)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1000-1:5000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:3,000-1:10,000

-

Immunocytochemistry (ICC/IF)

1:500

-

Flow Cytometry (Flow)

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PDH0-04

Immunogen

Synthetic peptide within C terminal human SOX10 aa 457-466/466. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SOX10,uniProtId:P56693-1,ncbiNodeId:9606,antigenRange:457-466,antigenLength:466,antigenImageFileName:MA5-50755_SOX10_P56693-1_Rabbit.svg,antigenImageFileNamePDP:MA5-50755_SOX10_P56693-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3094134

Product Specific Information

Positive control: A375 cell lysate, B16F1 cell lysate, human malignant melanoma tissue, human breast tissue, human breast carcinoma tissue, rat cerebellum tissue, mouse brain tissue, A375, B16F1.

Predicted band size: 50 kDa

Subcellular Location: Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus.

Target Information

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.