Thermo Fisher Scientific HLA-DP Recombinant Rabbit Monoclonal Antibody (PD00-70)
HLA-DP 단백질을 인식하는 재조합 토끼 단일클론 항체로, IHC(P) 및 유세포분석에 적합. 인간 시료 반응성, Protein A 정제, 액상 형태. 면역펩타이드 분석 및 항원 제시 연구에 활용 가능. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Flow Cytometry (Flow) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-70 |
| Immunogen | Synthetic peptide aa 1–260/260 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092887 |
Product Specific Information
- Positive control: Human tonsil tissue, human diffuse large B-cell lymphoma tissue, Daudi
- Predicted band size: 29 kDa
- Subcellular Location: Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome membrane, Lysosome membrane
Target Information
The human MHC class II is encoded by three different isotypes: HLA-DR, HLA-DQ, and HLA-DP, all of which are highly polymorphic. HLA-DP molecules are a protein complex found on the surface of antigen-presenting cells such as dendritic cells, macrophages, and B cells. Their main function is to present extracellular protein-derived peptides to CD4+ T cells for immune recognition.
HLA and MHC antibodies play an important role in immunopeptidomics, enabling identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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