Thermo Fisher Scientific TRAP220 Polyclonal Antibody
TRAP220 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 제품. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 664–720 of human TRAP220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553413 |
Product Specific Information
- Detects endogenous TRAP220 protein at a molecular weight of approximately 170 kDa.
- Purity >95% by SDS-PAGE.
Target Information
TRAP220 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator acts as a bridge conveying information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. It is recruited to promoters by direct interaction with regulatory proteins and serves as a scaffold for assembly of a functional preinitiation complex with RNA polymerase II and general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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