Thermo Fisher Scientific Phospho-Oxytocin Receptor (Thr235) Polyclonal Antibody
Phospho-Oxytocin Receptor (Thr235) 항체로, 인산화된 Thr235 부위의 OXTR 단백질을 특이적으로 검출합니다. WB 및 IHC(P) 실험에 적합하며, Human, Mouse, Rat 시료에서 반응합니다. Rabbit Polyclonal IgG 형식으로 PBS/glycerol buffer에 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OXTR (Accession P30559), corresponding to amino acid residues around phosphorylated Thr235. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816584 |
Product Specific Information
This antibody detects endogenous levels of Oxytocin Receptor only when phosphorylated at Thr235.
Target Information
The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins that activate a phosphatidylinositol-calcium second messenger system. The receptor consists of 389 amino acids with a molecular weight of approximately 43 kDa. The oxytocin–oxytocin receptor system plays a crucial role in uterine contractions during parturition and milk ejection. Oxytocin receptors are expressed in the mammary gland myoepithelial cells, and in the myometrium and endometrium of the uterus near term. Additionally, oxytocin receptors are found in the central nervous system, mediating maternal behavior, bonding, social memory, recognition, sexual and aggressive behaviors, and responses to stress and anxiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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