Thermo Fisher Scientific H3K122ac Polyclonal Antibody
H3K122ac 폴리클로날 항체로 인간, 마우스, 랫트 시료에서 사용 가능. Western blot과 IHC(P) 적용. Histone H3의 Lys122 아세틸화된 형태를 특이적으로 검출. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Histone H3 (Accession P68431), corresponding to amino acid residues N109–E134. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816581 |
Product Specific Information
Antibody detects endogenous levels of Acetyl-Histone H3 only when acetylated at Lys122.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translationally, histones are modified in various ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes, including methylation, acetylation, and phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-105108_H3K122ac_P68431-1_Rabbit.svg
- PA5-105108_H3K122ac_P68431-1_Rabbit_PDP.jpeg
- PA5-105108_H3K122ac_Q71DI3-1_Rabbit.svg
- PA5-105108_H3K122ac_Q71DI3-1_Rabbit_PDP.jpeg
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