Thermo Fisher Scientific Phospho-Histone H4 (Tyr89) Polyclonal Antibody
Phospho-Histone H4 (Tyr89) 폴리클로날 항체로, 인산화된 Tyr89 부위의 Histone H4를 특이적으로 검출. Western blot 및 IHC(파라핀 절편)에 적합. Rabbit IgG 기반의 액상 항체로, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Histone H4 (Accession P62805), corresponding to amino acid residues around phosphorylated Tyr89 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816578 |
Product Specific Information
Antibody detects endogenous levels of Histone H4 only when phosphorylated at Tyr89.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction into higher-order structures.
This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but contain a palindromic termination element. This gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체의 Immunogen 관련 이미지: PA5-105105_Histone_H4_P62805-1_Rabbit.svg, PA5-105105_Histone_H4_P62805-1_Rabbit_PDP.jpeg)
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