
Thermo Fisher Scientific Phospho-KIF1C (Ser1092) Polyclonal Antibody
KIF1C 단백질의 Ser1092 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합. 인간, 생쥐, 랫트 반응성. 고순도 정제 및 안정적 PBS/glycerol 저장 조건 제공.
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Thermo Fisher Scientific Phospho-KIF1C (Ser1092) Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIF1C (Accession O43896), corresponding to amino acid residues around phosphorylated Ser1092 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817228 |
Product Specific Information
This antibody detects endogenous levels of KIF1C only when phosphorylated at Ser1092.
Target Information
Kinesins are microtubule-dependent motor proteins responsible for organelle and vesicle transport within cells. KIF1C, a member of the KIF1/Unc104 family, is involved in mitochondrial or synaptic vesicle transport in axons.
Human KIF1C maps to chromosome 17p13 and encodes a 1,103 amino acid protein highly expressed in heart and skeletal muscle. Tyrosine phosphorylation regulates KIF1C-mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum.
KIF1C forms homodimers and associates with 14-3-3 proteins (beta, gamma, epsilon, zeta). In mouse macrophages, KIF1C contributes to anthrax lethal toxin resistance.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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