Thermo Fisher Scientific Phospho-KIF1C (Ser1092) Polyclonal Antibody
KIF1C 단백질의 Ser1092 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합. 인간, 생쥐, 랫트 반응성. 고순도 정제 및 안정적 PBS/glycerol 저장 조건 제공.
- 카탈로그번호
- PA5105829
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-KIF1C (Ser1092) Polyclonal Antibody
Thermo Fisher Scientific Phospho-KIF1C (Ser1092) Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIF1C (Accession O43896), corresponding to amino acid residues around phosphorylated Ser1092 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817228 |
Product Specific Information
This antibody detects endogenous levels of KIF1C only when phosphorylated at Ser1092.
Target Information
Kinesins are microtubule-dependent motor proteins responsible for organelle and vesicle transport within cells. KIF1C, a member of the KIF1/Unc104 family, is involved in mitochondrial or synaptic vesicle transport in axons.
Human KIF1C maps to chromosome 17p13 and encodes a 1,103 amino acid protein highly expressed in heart and skeletal muscle. Tyrosine phosphorylation regulates KIF1C-mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum.
KIF1C forms homodimers and associates with 14-3-3 proteins (beta, gamma, epsilon, zeta). In mouse macrophages, KIF1C contributes to anthrax lethal toxin resistance.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.