Thermo Fisher Scientific TNF alpha Monoclonal Antibody (TN3-19.12), FITC, eBioscience
Mouse, Rat TNF alpha 인식하는 중화용 단클론 항체로 FITC 형광 표지되어 있음. Flow cytometry, ELISA, neutralization 실험에 적합. 0.5 mg/mL 농도, PBS buffer에 0.09% sodium azide 포함. 4°C 암소 보관, 동결 금지.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific TNF alpha Monoclonal Antibody (TN3-19.12), FITC, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Flow Cytometry (Flow) | 0.25 µg/test | View 3 publications |
| ELISA | - | View 1 publication |
| Neutralization | - | View 2 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Recommended Isotype Control | Armenian Hamster IgG Isotype Control (eBio299Arm), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TN3-19.12 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_465427 |
Available Formats
Product Specific Information
The TN3-19.12 monoclonal antibody reacts with mouse, rat, and rabbit TNF alpha, but not with human TNF alpha. It is a neutralizing antibody. Mouse TNF alpha (17 kDa) is produced by macrophages, monocytes, neutrophils, CD4+ T cells, and NK cells. A 26 kDa membrane-bound form also exists. TNF alpha plays a key role in immune regulation and cytolysis, forming dimers and trimers.
Applications Reported:
Used for intracellular staining in flow cytometric analysis, cytokine neutralization, and ELISA. FITC conjugated TN3-19.12 is recommended for flow cytometry. Functional Grade purified TN3-19.12 (Product #00-4956-58) can be used ≤20 µg/mL. Titrate antibody for optimal performance.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
TNF alpha is a multifunctional proinflammatory cytokine of the TNF superfamily, mainly secreted by macrophages. It binds TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR receptors and regulates immune cells, proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha forms multimers (2–5 units) and shows a 17 kDa band in SDS-PAGE under non-reducing conditions. Knockout studies indicate neuroprotective functions and tumor necrosis effects. It is involved in immune responses against infections and tumor cytolysis, acting synergistically with interferon-gamma. TNF alpha is implicated in autoimmune diseases, insulin resistance, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific TNF alpha Monoclonal Antibody (MAb11), FITC, eBioscience
163,300원
Thermo Fisher Scientific
Thermo Fisher Scientific GM-CSF Monoclonal Antibody (MP1-22E9), FITC, eBioscience
341,200원
Thermo Fisher Scientific
Thermo Fisher Scientific TNF alpha Monoclonal Antibody (TN3-19.12), FITC, eBioscience
372,500원
Thermo Fisher Scientific
Thermo Fisher Scientific IFN gamma Monoclonal Antibody (XMG1.2), FITC, eBioscience
191,600원
Thermo Fisher Scientific
Thermo Fisher Scientific IFN gamma Monoclonal Antibody (4S.B3), FITC, eBioscience
221,900원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|