Thermo Fisher Scientific NDUFV3 Polyclonal Antibody
Thermo Fisher Scientific의 NDUFV3 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 고순도 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 미토콘드리아 복합체 I 연구에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human NDUFV3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719619 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH produced in the Krebs cycle, this complex reduces ubiquinone to ubiquinol, initiating electron transfer to successive complexes and leading to oxygen reduction to water.
Mitochondrial complex I consists of over 40 subunits and is clinically significant, as defects in any subunit can cause various myopathies and neuropathies.
NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also known as NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein believed not to be directly involved in catalysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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