Thermo Fisher Scientific MRPS5 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.

Target Information

Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both composed of multiple mitochondrial ribosomal proteins (MRPs) encoded by nuclear genes. These proteins are essential for mitochondrial protein synthesis. MRP-S5 (mitochondrial ribosomal protein S5), also known as S5mt, is a 430 amino acid mitochondrial protein belonging to the ribosomal protein S5P family and is a component of the 28S subunit. MRP-S5 contains one S5 DRBM domain and exists as two alternatively spliced isoforms. The gene encoding MRP-S5 maps to human chromosome 2, which contains approximately 237 million bases, encodes over 1,400 genes, and constitutes about 8% of the human genome. Several genetic diseases are associated with genes on chromosome 2, including Harlequin ichthyosis, sitosterolemia, and Alstrom syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.