Thermo Fisher Scientific IgA (Immunoglobulin Alpha Heavy Chain) (B-Cell Marker) Monoclonal Antibody (HISA43)
IgA (Immunoglobulin Alpha Heavy Chain) 단일클론 항체로 B세포 마커 분석에 적합. IHC, ICC/IF, Flow Cytometry 등 다양한 응용 가능. Human 반응성, Mouse IgG1, kappa 아이소타입. 고순도 Protein A/G 정제, 1 mg/mL 농도, 보존제 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HISA43 |
| Immunogen | Purified human IgA (Heavy Chain) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Constant region of immunoglobulin heavy chains. Immunoglobulins (antibodies) are membrane-bound or secreted glycoproteins produced by B lymphocytes.
During the recognition phase of humoral immunity, membrane-bound immunoglobulins serve as receptors that trigger clonal expansion and differentiation of B lymphocytes into plasma cells upon antigen binding.
Secreted immunoglobulins mediate the effector phase, eliminating bound antigens.
Each immunoglobulin has two antigen-binding sites formed by the variable domains of heavy and light chains.
Variable domains are assembled by V-(D)-J rearrangement and undergo somatic hypermutation for affinity maturation.
IgA is the major immunoglobulin class in body secretions.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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