Thermo Fisher Scientific MTF1 Monoclonal Antibody (OTI7D6), TrueMAB
MTF1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot과 IHC(P)에서 검증됨. Human 시료 반응성. Lyophilized 형태로 제공되며 PBS, 8% trehalose buffer에 보관. 금속 항상성 관련 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–272 of human MTF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The MTF1 gene encodes a transcription factor that regulates expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver.
MTF1 is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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