Thermo Fisher Scientific CCR3 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 10 µg/mL

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
• Percent identity with other species by BLAST analysis: Human (100%), Gorilla, Gibbon, Monkey (88%).

Target Information

CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta.
CCR3 transduces a signal by increasing intracellular calcium ion levels and serves as an alternative co-receptor with CD4 for HIV-1 infection.
Chemokines play essential roles in inflammation and immune cell recruitment. They activate leukocytes via G protein-coupled receptors.
Chemokine receptors are classified into two major groups: CXCR and CCR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.