
Thermo Fisher Scientific CCR3 Polyclonal Antibody
CCR3 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, IHC 및 ELISA에 적합합니다. 인간 CCR3에 대한 높은 특이성과 교차 반응 분석 정보 제공. 액상 형태로 1 mg/mL 농도, 2–8°C 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd extracellular domain of human CCR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long term storage store at -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2550159 |
Product Specific Information
- In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
- Percent identity with other species by BLAST analysis: Human (100%), Gorilla, Gibbon, Monkey (88%).
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta.
CCR3 transduces a signal by increasing intracellular calcium ion levels and serves as an alternative co-receptor with CD4 for HIV-1 infection.
Chemokines play essential roles in inflammation and immune cell recruitment. They activate leukocytes via G protein-coupled receptors.
Chemokine receptors are classified into two major groups: CXCR and CCR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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