Thermo Fisher Scientific CCR10 Polyclonal Antibody
Thermo Fisher Scientific의 CCR10 Polyclonal Antibody는 인간 CCR10 단백질을 인식하는 토끼 IgG 기반 항체로, IHC(P) 및 ELISA에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로 피부 염증 관련 CCR10-CCL27 경로 분석에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 5 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminus of human CCR10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550158 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Rabbit (94%); Bat, Pig (88%); Rat (82%) - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Chemokines are small (approximately 8–14 kD), mostly basic, structurally related molecules that regulate leukocyte trafficking through interactions with 7-transmembrane, G protein-coupled receptors.
They play key roles in immune system development, homeostasis, and function, and also affect central nervous system cells and endothelial cells involved in angiogenesis or angiostasis.
Chemokines are divided into two major subfamilies, CXC and CC, based on cysteine residue arrangement.
CCR10 is the receptor for CCL27, and CCR10–CCL27 interactions are involved in T cell-mediated skin inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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