Thermo Fisher Scientific KPNA5 Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 5 µg/mL

Product Specifications

Product Specific Information

• Suggested positive control: human testis tissue
• PA5-34371 can be used with blocking peptide PEP-1414

Target Information

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), consisting of 60–100 proteins and approximately 120 million daltons in size.
Small molecules (up to 70 kD) pass through the nuclear pore by nonselective diffusion, while larger molecules are transported actively.
Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs).
KPNA5 belongs to the importin alpha protein family and is involved in NLS-dependent protein import into the nucleus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.