Thermo Fisher Scientific WDR35 Polyclonal Antibody
인간 WDR35 단백질을 인식하는 토끼 폴리클로날 항체. IHC에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 냉장 보관 시 3개월 안정, 장기 보관은 -20°C 권장. 연구용으로만 사용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid synthetic peptide near the amino terminus of human WDR35 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551722 |
Product Specific Information
- Suggested positive control: human testis tissue
- PA5-34370 can be used with blocking peptide PEP-1413
Target Information
WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have diverse functions such as signal transduction, cell cycle regulation, RNA splicing, and transcription.
WDR35 (also known as CED2) mutations are associated with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disorder characterized by craniosynostosis and ectodermal and skeletal abnormalities.
WDR35 localizes to cilia and centrosomes during embryogenesis. Human and mouse fibroblasts lacking this gene fail to produce cilia. Mutations can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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