Thermo Fisher Scientific Insulin Receptor Polyclonal Antibody, Biotin
인슐린 수용체를 인식하는 비오틴 결합 토끼 폴리클로날 항체. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제 제품으로 안정적이며 연구용으로만 사용 가능.
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Thermo Fisher Scientific Insulin Receptor Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 950–1000 on human Insulin Receptor (transcript variant 2 protein) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine residues in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are associated with various insulin resistance syndromes, while IGF-1R defects may contribute to certain forms of growth retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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