Thermo Fisher Scientific Insulin Receptor Polyclonal Antibody, FITC
FITC 형광 표지된 Insulin Receptor 폴리클로날 항체로 Western blot, IHC, ELISA, IP 등에 사용 가능. 사람, 생쥐, 원숭이, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Insulin Receptor Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 950–1000 on human Insulin receptor (transcript variant 2 protein) |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
INSR (Insulin Receptor) is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are associated with various insulin resistance syndromes, and IGF-1R defects may cause certain forms of growth retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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