Thermo Fisher Scientific Urocortin Polyclonal Antibody
Urocortin 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제, PBS/glycerol 완충액에 보존. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 80–124 of Human UCN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718917 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Urocortin (UCN) is a 40-amino-acid neuropeptide widely distributed in the central nervous system (CNS). It belongs to a family of peptides structurally related to corticotrophin releasing factor (CRF), sauvagine, and urotensin I. Urocortin is derived from a larger precursor protein, pro-urocortin (also known as corticotensin). It exhibits biological actions similar to CRF, including stress-related endocrine, autonomic, and behavioral responses in mammals. Urocortin is a potent stimulator of adrenocorticotropic hormone (ACTH) secretion by corticotroph cells from the anterior pituitary both in vitro and in vivo.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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