Thermo Fisher Scientific MUC20 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  PNFMVLIATS VETSAASGSP EGAGMTTVQT ITGSDPEEAI FDTLCTDDSS EEAKTLTMDI LTLAHTSTEA KGLSSESSAS SDGPHPVITP SRASESSASS D
• Positive Samples: 293T, A-549, DU145, LO2, U-251MG, HT-29, Mouse kidney, Mouse lung, Rat kidney
• Cellular Location: Apical cell membrane, Basolateral cell membrane, Cell projection, microvillus membrane

Target Information

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier.
The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted.
The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades.
The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies.
Multiple transcript variants encoding different isoforms have been found for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.