Thermo Fisher Scientific CHRM1 Polyclonal Antibody
CHRM1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 251–350 of human CHRM1 (NP_000729.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806269 |
Product Specific Information
- Positive Samples: U-87MG, HepG2
- Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
- Immunogen sequence:
SPETPPGRCC RCCRAPRLLQ AYSWKEEEEE DEGSMESLTS SEGEEPGSEV VIKMPMVDPE AQAPTKQPPR SSPNTVKRPT KKGRDRAGKG QKPRGKEQLA
Target Information
Muscarinic cholinergic receptors are G protein-coupled receptors responsible for diverse cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. CHRM1 plays a role in vagally-induced bronchoconstriction and gastric acid secretion. The CHRM1 gene is localized to chromosome 11q13.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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