Thermo Fisher Scientific PUS10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 290-529 of human PUS10 (NP_6533102) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PUS10,uniProtId:Q3MIT2-1,ncbiNodeId:9606,antigenRange:290-529,antigenLength:529,antigenImageFileName:PA5-90861_PUS10_Q3MIT2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90861_PUS10_Q3MIT2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.9 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806265

Product Specific Information

Immunogen sequence: VAGRYNKYSR NLPQTPWIID GERKLESSVE ELISDHLLAV FKAESFNFSS SGREDVDVRT LGNGRPFAIE LVNPHRVHFT SQEIKELQQK INNSSNKIQV RDLQLVTREA IGHMKEGEEE KTKTYSALIW TNKAIQKKDI EFLNDIKDLK IDQKTPLRVL HRRPLAVRAR VIHFMETQYV DEHHFRLHLK TQAGTYIKEF VHGDFGRTKP NIGSLMNVTA DILELDVESV DVDWPPALDD; Positive Samples: Mouse thymus, Mouse spleen, Mouse testis, Rat thymus

Target Information

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.