Thermo Fisher Scientific CD209 Polyclonal Antibody
CD209 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 ELISA에 사용 가능하며, 인간, 생쥐, 랫트 반응성을 갖습니다. 단백질 A로 정제된 액상 형태로 보관은 -20°C에서 유지합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse DC-SIGN/CD209, amino acids 81–180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a transmembrane receptor commonly referred to as DC-SIGN, expressed on dendritic cells and macrophages. It plays a key role in the innate immune system by recognizing diverse pathogens including parasites and viruses. The protein has three main domains: an N-terminal transmembrane domain, a tandem-repeat neck domain, and a C-type lectin carbohydrate recognition domain. The extracellular region functions as both a pathogen recognition and cell adhesion receptor. The neck region enables homo-oligomerization, enhancing multivalent ligand binding. Variations in the neck domain repeats can affect ligand-binding ability. DC-SIGN is closely related to L-SIGN (GeneID 10332) but differs in ligand-binding properties and tissue distribution. Alternative splicing generates multiple variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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