Thermo Fisher Scientific Phospho-CK1 gamma (Tyr263) Polyclonal Antibody
Rabbit 폴리클로날 항체로 CK1 gamma (Tyr263) 인산화 부위를 특이적으로 인식합니다. IHC 및 peptide-ELISA에 적합하며 높은 민감도와 특이성을 제공합니다. 연구용으로만 사용되며, -20°C에서 안정적으로 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Peptide-ELISA (pep-ELISA) | 1:20,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263 (E-R-YP-Q-K) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556285 |
Target Information
Casein kinase I (CKI) and casein kinase II (CKII) are families of serine/threonine protein kinases found in all eukaryotes.
CKI family members (α, γ, ε, δ) regulate cytoplasmic and nuclear processes such as DNA replication and repair.
CKII typically forms a tetrameric complex (α2β2 or αα'β2), where the α catalytic subunit is activated by the β regulatory subunit that undergoes autophosphorylation.
CKII activity is high in proliferating and differentiating cells and phosphorylates over 100 substrates, including nuclear oncoproteins, transcription factors, and DNA metabolism enzymes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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