Thermo Fisher Scientific EphB Pan Polyclonal Antibody
EphB 수용체를 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합합니다. 인간 EphB1/2/3/4의 Tyr600/602/614/596 부위에서 유래한 합성 펩타이드로 면역화되었습니다. 비결합형 액상 형태이며 농도는 1 mg/mL입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA539736
- 판매단위
- pk
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Thermo Fisher Scientific EphB Pan Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic non-phosphopeptide derived from human EPHB1/2/3/4 around the phosphorylation site of Tyr600/602/614/596 (F-T-YP-E-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556287 |
Target Information
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.
The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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