
Thermo Fisher Scientific GABBR2 Monoclonal Antibody (N81/2), PerCP
GABBR2 단백질 검출용 PerCP 결합 단일클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 단백질 G 정제, 보존제 무첨가 액상 형태. 4°C 보관, 연구용 전용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N81/2 |
| Immunogen | Fusion protein amino acids 861–912 of rat GABA(B)R2 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931989 |
Additional Formats
Product Specific Information
- 1 µg/mL of MA5-45535 was sufficient for detection of GABA(B)R2 in 20 µg of rat brain membrane lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 105 kDa. No cross-reactivity against GABA(B)R1.
- This antibody was formerly sold as clone S81-2.
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release and ion channel activity.
This receptor forms an active heterodimeric complex with GABA-B receptor subunit 1, and both subunits are required for activity.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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