Thermo Fisher Scientific Erk1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Erk1 (MAPK3), reactive with human, mouse, and rat. Validated for WB and IHC applications. Lyophilized form, unconjugated, no preservative. Ideal for studying MAPK signaling and cellular processes.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 300–360 of mouse Erk1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Erk1.
Target Information
MAPK3 (ERK1) is a serine/threonine kinase that activates p90, RSK, MSK, ELK1, and Stat3, functioning within the MAPK pathway. ERK1 is widely expressed and regulates meiosis, mitosis, and post-mitotic functions in differentiated cells. It responds to diverse stimuli such as growth factors, cytokines, viral infection, and G protein-coupled receptor ligands, activating ERK1/ERK2 pathways. ERK1 participates in signaling cascades controlling proliferation, differentiation, and cell cycle progression. Activated ERK1 translocates to the nucleus to phosphorylate nuclear targets. Alternatively spliced transcript variants encoding different ERK1 isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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