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Thermo Fisher Scientific ERK1/2 Polyclonal Antibody
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ERK1/2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. Lyophilized 형태로 보존, 장기 보관 시 -20°C 권장. ERK1/2 신호전달 연구용.
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마지막 업데이트 2025. 08. 05. 오후 08:00
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Thermo Fisher Scientific OSE00039W-100UL ERK1/2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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563,100원VAT 포함 619,410원
Thermo Fisher Scientific · Thermo Fisher Scientific ERK1/2 Polyclonal Antibody
Thermo Fisher Scientific ERK1/2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 300–355 of mouse Erk2 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen shares 80% identity with Erk1.
- Specificity: Erk2 and Erk1.
Target Information
ERK1 and ERK2 are widely expressed and regulate meiosis, mitosis, and postmitotic functions in differentiated cells.
They are activated by various stimuli such as growth factors, cytokines, viral infection, and G protein-coupled receptor ligands.
Upon activation, Raf phosphorylates MEK1/2, which in turn phosphorylates ERK1/2. Activated ERKs phosphorylate cytoplasmic targets or migrate to the nucleus to activate transcription factors such as c-Fos and Elk-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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