Thermo Fisher Scientific Phospho-MEK5 (Ser311, Thr315) Polyclonal Antibody
Phospho-MEK5 (Ser311, Thr315) 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 사용 가능. Human, Mouse, Rat 반응성. PBS, 50% glycerol buffer에 보관되며 -20°C에서 저장. 세포 신호전달 연구 및 MEK5 관련 단백질 분석에 적합.
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Applications
- Western Blot (WB): 1:500–1:1,000
Suggested positive control: rat or mouse brain cells.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine 311 and Threonine 315 (V-N-S(p)I-A-K-T(p)-Y-V) derived from Rat MEK5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554309 |
Product Specific Information
A suggested positive control for Western blot is rat or mouse brain cells.
Target Information
MAP2K5 (MEK5) serine/threonine kinase, also known as mitogen-activated protein kinase 5, is a dual specificity protein kinase that interacts with and activates MAPK7/ERK5. It can be phosphorylated and activated by MAP3K3/MEKK3 and atypical PKC isoforms (aPKCs). The MAP2K5-mediated signaling cascade is involved in growth factor–stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may influence colorectal cancer risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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