Thermo Fisher Scientific KCNJ3 Monoclonal Antibody (OTI1G2), TrueMAB
인간 KCNJ3 단백질을 인식하는 마우스 단클론 항체로, WB, ICC/IF, Flow Cytometry에 적합. 무보존제 동결건조 형태로 제공되며, 재용해 후 1 mg/mL 농도로 사용 가능. 심박 조절 관련 칼륨 채널 연구용으로 최적화된 TrueMAB 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 279–501 of human KCNJ3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, channel opening shifts to more positive voltages. Inward rectification is mainly due to blockage of outward current by internal magnesium. This receptor plays an essential role in regulating the heartbeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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