Thermo Fisher Scientific ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/3260)
인간 ICOS-L/ICOS Ligand(B7RP-1)을 인식하는 마우스 단클론 항체로, 면역조직화학(IHC), ELISA, 펩타이드 어레이 등에 사용 가능. Protein A/G 정제, PBS 완충액에 0.05% BSA 및 sodium azide 포함. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | - |
| ELISA | Assay-dependent | - |
| Peptide Array | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICOSL/3260 |
| Immunogen | Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 23–149) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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