Thermo Fisher Scientific ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/3111)
ICOSL/3111 단클론 항체는 인간 ICOS-L/B7RP-1 단백질을 표적으로 하는 마우스 IgG1 항체입니다. IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 면역 분석에 사용 가능합니다. 고순도 Protein A/G 정제, PBS 버퍼, 보존제 무첨가로 연구용에 적합합니다.
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Thermo Fisher Scientific ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/3111)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICOSL/3111 |
| Immunogen | Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 23–149) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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