Thermo Fisher Scientific ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Monoclonal Antibody (ICOSL/7700)
ICOSL/7700 단클론 항체는 인간 ICOS Ligand(B7RP-1)를 표적으로 하는 면역항암 연구용 항체입니다. IHC(P)에서 검증되었으며, 단클론 Mouse IgG2b 형식으로 제공됩니다. Protein A/G 정제, 200 µg/mL 농도, PBS/BSA buffer에 보관됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICOSL/7700 |
| Immunogen | Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 1–300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: HL60, HuT78, or HUVEC lysates (WB); Human tonsil tissue (IHC); U937
- Cellular Location: Cell surface, cytoplasm
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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