Thermo Fisher Scientific Phospho-ARHGAP42 (Tyr376) Polyclonal Antibody
ARHGAP42 단백질의 Tyr376 인산화 상태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot에서 사용 가능하며, 인간과 생쥐 시료에 반응. 고순도 정제 및 PBS/glycerol 완충액에 보관. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARHGAP42 (Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr376. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816797 |
Product Specific Information
Antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr376.
Target Information
This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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