Thermo Fisher Scientific Phospho-ARHGAP42 (Tyr376) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ARHGAP42(Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr376. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARHGAP42,uniProtId:A6NI28-1,ncbiNodeId:9606,antigenRange:376,antigenLength:874,antigenImageFileName:PA5-105369_ARHGAP42_A6NI28-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105369_ARHGAP42_A6NI28-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816797

Product Specific Information

Antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr376.

Target Information

This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.