Thermo Fisher Scientific Gelsolin Recombinant Rabbit Monoclonal Antibody (5O10O1)
Western blot, IHC, ELISA에 적합한 Gelsolin 단백질 검출용 토끼 단클론 항체. 인간 및 마우스 반응성. HEK293 세포에서 발현된 재조합 항체로 높은 특이성과 재현성 제공. PBS 기반 완충액에 보관하며 -20°C에서 안정적 유지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5O10O1 |
| Immunogen | A synthetic peptide corresponding to amino acids 400–500 of human Gelsolin (NP_000168.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS (pH 7.3) with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911928 |
Product Specific Information
- Positive test controls: C2C12, Mouse lung, HeLa, A-549, RD
- Subcellular localization: Cytoplasm, Secreted, Cytoskeleton
- Immunogen sequence:
DQTDGLGLSY LSSHIANVER VPFDAATLHT STAMAAQHGM DDDGTGQKQI WRIEGSNKVP VDPATYGQFY GGDSYIILYN YRHGGRQGQI IYNWQGAQST Q
Target Information
The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. This calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are associated with familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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