Thermo Fisher Scientific IFITM2 Monoclonal Antibody (OTI6F7), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

IFN-induced antiviral protein that inhibits viral entry into the host cell cytoplasm. It allows endocytosis but prevents viral fusion and release of viral contents into the cytosol.
Active against multiple viruses, including:

• Influenza A virus
• SARS coronavirus (SARS-CoV)
• Marburg virus (MARV)
• Ebola virus (EBOV)
• Dengue virus (DNV)
• West Nile virus (WNV)
• HIV-1
• Vesicular stomatitis virus (VSV)

It can inhibit viral entry mediated by influenza hemagglutinin, MARV and EBOV GP1,2, SARS-CoV S protein, and VSV G protein.
Also induces cell cycle arrest and mediates apoptosis via caspase activation in a p53-independent manner.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.