Thermo Fisher Scientific Pan-cadherin Recombinant Rabbit Monoclonal Antibody (ST54-01)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

Flow Cytometry (Flow)

1:50-1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ST54-01

Immunogen

Synthetic peptide within C-terminal human CDH2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Pan-cadherin,uniProtId:P19022-1,ncbiNodeId:9606,antigenRange:906,antigenLength:906,antigenImageFileName:MA5-41143_Pan-cadherin_P19022-1_Rabbit.svg,antigenImageFileNamePDP:MA5-41143_Pan-cadherin_P19022-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:Pan-cadherin,uniProtId:P12830-1,ncbiNodeId:9606,antigenRange:882,antigenLength:882,antigenImageFileName:MA5-41143_Pan-cadherin_P12830-1_Rabbit.svg,antigenImageFileNamePDP:MA5-41143_Pan-cadherin_P12830-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:Pan-cadherin,uniProtId:P22223-1,ncbiNodeId:9606,antigenRange:829,antigenLength:829,antigenImageFileName:MA5-41143_Pan-cadherin_P22223-1_Rabbit.svg,antigenImageFileNamePDP:MA5-41143_Pan-cadherin_P22223-1_Rabbit_PDP.jpeg,sortOrder:3},{targetFamily:Pan-cadherin,uniProtId:P55283-1,ncbiNodeId:9606,antigenRange:916,antigenLength:916,antigenImageFileName:MA5-41143_Pan-cadherin_P55283-1_Rabbit.svg,antigenImageFileNamePDP:MA5-41143_Pan-cadherin_P55283-1_Rabbit_PDP.jpeg,sortOrder:4}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2898897

Target Information

Pan Cadherin including CDH1, CDH2, CDH3, CDH4 protein belong to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin`s function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.