Thermo Fisher Scientific Phospho-CDC37 (Ser13) Recombinant Rabbit Monoclonal Antibody (SD08-50)
Phospho-CDC37 (Ser13) 특이성을 가진 재조합 토끼 단클론 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot에 최적화되어 있으며, 고순도의 Protein A 정제 항체입니다. 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB): 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD08-50 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser13 of human CDC37 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898899 |
Target Information
In S. cerevisiae, Cdc37 acts as an important regulator of the cell division cycle by modulating cyclin-dependent kinases (CDKs). It is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase.
Cdc37 has been identified as the same protein previously described as p50, which interacts with many of the same proteins as HSP90. Complexes include Src-family kinases (Fyn, Yes, Fes, Lck, Fgr), Raf, and pp60v-src.
Cdc37 functions as a chaperone independently and in concert with HSP90, and is essential for HSP90 binding to Cdk4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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