Thermo Fisher Scientific CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), APC, eBioscience
인간 CD29(Integrin beta 1)을 인식하는 TS2/16 단클론 항체로, APC 형광체가 결합되어 있습니다. Flow Cytometry에 최적화되어 있으며, 5 µL/test로 사용됩니다. 세포 부착 및 이동 관련 연구에 적합하며, 4°C 암조건에서 보관합니다.
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Thermo Fisher Scientific CD29 (Integrin beta 1) Monoclonal Antibody (TS2/16), APC, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.5 µg)/test
Publications: View 20 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TS2/16 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1659685 |
Available Formats
- Unconjugated
- FITC
- NovaFluor Blue 510
- NovaFluor Blue 660-120S
- NovaFluor Red 710
- NovaFluor Yellow 590
- NovaFluor Yellow 610
- PE
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 645
- Super Bright 702
- Request custom conjugation
Product Specific Information
Description:
The TS2/16 monoclonal antibody reacts with human CD29 (Integrin beta 1), a 130 kDa transmembrane glycoprotein that forms heterodimers with integrin alpha subunits to create the VLA (Very Late Antigen) adhesion molecule family. These integrins mediate cell-cell and cell-matrix interactions. CD29 is expressed broadly on lymphocytes and monocytes, with lower expression on granulocytes. The TS2/16 antibody exhibits activating activity for beta 1 integrins.
Applications Reported:
Reported for use in flow cytometric analysis.
Applications Tested:
Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. Use at 5 µL (0.5 µg) per test (100 µL final volume). Recommended cell number: 10⁵–10⁸ cells/test.
Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
ITGB1 (Integrin Subunit Beta 1, CD29):
A 110 kDa cell surface glycoprotein expressed by various cell types including all leukocytes. Forms non-covalent heterodimers with multiple alpha chains (α1–α6), determining binding properties of VLA integrins. Functions in cell adhesion and migration.
Decreased ITGB1 expression correlates with multidrug resistance in tumor cells. Up-regulated during leukocyte migration and involved in immune cell trafficking, tissue damage, and inflammatory bowel disease.
Two major forms, beta1A and beta1D, differ by 13 amino acids and show tissue-specific distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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