
Thermo Fisher Scientific OTX2 Monoclonal Antibody (OTI1B2), TrueMAB
OTX2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화됨. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며, PBS 및 trehalose 완충액 포함. 연구용으로 뇌 및 감각기관 발달 관련 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B2 |
| Immunogen | Full length human recombinant protein of human OTX2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
OTX2 is a 289 amino acid protein belonging to the bicoid sub-family of homeodomain-containing transcription factors.
It has two known splice variants with distinct isoforms, though other isoforms may exist.
OTX2 functions as an early marker of endodermal differentiation in embryonic stem cells and plays a role in brain and sensory organ development.
It may bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Defects in OTX2 are associated with microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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