Thermo Fisher Scientific Crystallin Alpha B Monoclonal Antibody (CPTC-CRYAB-1)
Crystallin Alpha B 단백질을 인식하는 mouse monoclonal antibody로, WB 및 IHC에 적합. 인간 및 랫트 반응성. 단백질 A/G로 정제된 액상형 항체이며, 4°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- 1410-MSM1-P1
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Crystallin Alpha B Monoclonal Antibody (CPTC-CRYAB-1)
Applications
| Application | Tested Dilution | Note |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPTC-CRYAB-1 |
| Immunogen | Recombinant human full-length CRYAB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 min.
Target Information
Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural role is to maintain the proper refractive index.
The mammalian lens contains three major classes of crystallins: alpha, beta, and gamma. Alpha-crystallin is the largest, composed of two primary gene products—alpha-A and alpha-B.
Alpha-B crystallin functions as a molecular chaperone, preventing aggregate formation that could lead to cataract development. It is also linked to Alexander’s disease, where it accumulates in brain cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.