Thermo Fisher Scientific Crystallin Alpha B Monoclonal Antibody (CRYAB/7918)
CRYAB 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 면역조직화학(IHC)에 적합합니다. 인간 시료에 반응하며, Protein A/G 정제된 액상 형태로 제공됩니다. PBS(pH 7.4) 완충액에 보존제 없이 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- 1410MSM18P1ABX
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Crystallin Alpha B Monoclonal Antibody (CRYAB/7918)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CRYAB/7918 |
| Immunogen | Recombinant human full-length CRYAB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Target Information
Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural function is to maintain the proper refractive index. The mammalian lens contains three major classes of crystallins: alpha, beta, and gamma.
Alpha-crystallin is the largest and composed of two primary gene products, alpha-A and alpha-B. Alpha-crystallin comprises about 40% of total lens protein composition and functions as a molecular chaperone, preventing aggregate formation that may lead to cataract formation.
Phosphorylated states of alpha-crystallin occur in response to cellular stress and may serve structural control functions in protein maintenance. Alpha-B crystallin has been linked to Alexander's disease, where it accumulates in brain cells of affected individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.