Thermo Fisher Scientific CD126 Monoclonal Antibody (D7715A7), PE, eBioscience
마우스 CD126(IL-6 receptor α chain)을 인식하는 단클론 항체로, PE 형광표지되어 있습니다. 유세포분석(Flow Cytometry)에 적합하며, 0.125 µg/test로 사용됩니다. 4°C 암소 보관, 동결 금지. 연구용으로만 사용 가능합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 0.125 µg/test
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Recommended Isotype Control | Rat IgG2b kappa Isotype Control (eB149/10H5), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D7715A7 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_996658 |
Additional Formats:
Product Specific Information
The monoclonal antibody D7715A7 recognizes mouse CD126, the IL-6 receptor alpha chain, a member of the Ig superfamily. CD126 can heterodimerize with CD130 (gp130) to form the high affinity IL-6 receptor. Upon IL-6 binding, signaling from the CD130 subunit is initiated and the receptor complex is internalized.
A soluble version of the IL-6 receptor also exists, which, when bound to IL-6, acts in trans to signal. Expression is found on peripheral T lymphocytes and during thymic development is restricted to SP populations. Additional expression occurs on activated B lymphocytes, macrophages, granulocytes, and CD34⁺ hematopoietic progenitor cells. The D7715A7 binding can be blocked by the addition of IL-6 ligand.
Applications Reported: Flow cytometric analysis
Applications Tested: Tested by flow cytometric analysis of mouse splenocytes.
Recommended ≤ 0.125 µg per test (100 µL final volume).
Cell number: 10⁵–10⁸ cells/test (empirically determined).
Excitation: 488–561 nm
Emission: 578 nm
Laser: Blue, Green, Yellow-Green
Filtration: 0.2 µm post-manufacturing filtered
Target Information
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the IL-6 receptor complex. IL-6 regulates cell growth and differentiation and plays an essential role in immune response.
The IL6 receptor complex includes IL6ST/GP130, a receptor subunit shared by many cytokines. Dysregulated IL6 and IL6R expression are implicated in diseases such as multiple myeloma, autoimmune disorders, and prostate cancer. Alternatively spliced variants and a pseudogene on chromosome 9 have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CD130 (GP130) Monoclonal Antibody (KGP130), PE, eBioscience
669,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Myeloperoxidase (MPO) Monoclonal Antibody (MPO455-8E6), PE, eBioscience
525,000원
Thermo Fisher Scientific
Thermo Fisher Scientific CD126 Monoclonal Antibody (D7715A7), PE, eBioscience
238,600원
Thermo Fisher Scientific
Thermo Fisher Scientific TF25 B A 208/60 P2 IPR ACOM
14,640,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CD127 Monoclonal Antibody (eBioSB/199 (SB/199)), PE, eBioscience
329,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|