
Thermo Fisher Scientific SDHB Recombinant Rabbit Monoclonal Antibody (ARC0733)
Thermo Fisher SDHB Recombinant Rabbit Monoclonal Antibody (ARC0733)는 인간, 마우스, 랫트 반응성을 가진 고순도 항체로, Western Blot과 ELISA에 최적화되어 있습니다. HEK293 발현 시스템에서 생산된 비결합 항체로, 안정적인 PBS/glycerol 버퍼에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0733 |
| Immunogen | Synthetic peptide corresponding to amino acids 181–280 of human SDHB (P21912) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849095 |
Product Specific Information
Immunogen sequence:
DGLYECILCA CCSTSCPSYW WNGDKYLGPA VLMQAYRWMI DSRDDFTEER LAKLQDPFSL YRCHTIMNCT RTCPKGLNPG KAIAEIKKMM ATYKEKKASV
Target Information
Complex II of the respiratory chain is involved in the oxidation of succinate and electron transfer from FADH to CoQ. It consists of four nuclear-encoded subunits localized in the mitochondrial inner membrane. The iron-sulfur subunit contains three cysteine-rich clusters forming the enzyme’s iron-sulfur centers. Mutations in this gene are associated with paragangliomas and pheochromocytoma, linking mitochondrial dysfunction to tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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