Thermo Fisher Scientific AKAP4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 189-340 of human AKAP4 (NP_003877.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AKAP4,uniProtId:Q5JQC9-1,ncbiNodeId:9606,antigenRange:189-340,antigenLength:854,antigenImageFileName:PA5-109377_AKAP4_Q5JQC9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109377_AKAP4_Q5JQC9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.64 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854788

Product Specific Information

Immunogen sequence: QSPSAPPAKP PSTQRAVISP DGECSIDDLS FYVNRLSSLV IQMAHKEIKE KLEGKSKCLH HSICPSPGNK ERISPRTPAS KIASEMAYEA VELTAAEMRG TGEESREGGQ KSFLYSELSN KSKSGDKQMS QRESKEFADS ISKGLMVYAN QV

Target Information

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.