Thermo Fisher Scientific ALDH1B1 Polyclonal Antibody
Thermo Fisher Scientific의 ALDH1B1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot, ICC/IF, ELISA에 적합합니다. Rabbit IgG 폴리클로날 항체로, ALDH1B1 단백질(aa 278-517)을 면역원으로 사용하였으며, 에탄올 해독 및 대사 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 278–517 of human ALDH1B1 (NP_000683.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.31 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854789 |
Product Specific Information
Immunogen sequence:
NLKRVTLELG GKSPSIVLAD ADMEHAVEQC HEALFFNMGQ CCCAGSRTFV EESIYNEFLE RTVEKAKQRK VGNPFELDTQ QGPQVDKEQF ERVLGYIQLG QKEGAKLLCG GERFGERGFF IKPTVFGGVQ DDMRIAKEEI FGPVQPLFKF KKIEEVVERA NNTRYGLAAA VFTRDLDKAM YFTQALQAGT VWVNTYNIVT CHTPFGGFKE SGNGRELGED GLKAYTEVKT VTIKVPQKNS
Target Information
Aldehyde dehydrogenases (ALDHs) mediate NADP⁺-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation, and metabolism of corticosteroids, biogenic amines, and neurotransmitters.
Alcohol drinking habits and cardiovascular disease risk factors may be associated with ALDH gene variants.
ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517 amino acid mitochondrial protein expressed mainly in the liver and testis, and to a lesser extent in the brain.
ALDH1B1 belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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