Thermo Fisher Scientific NPY Polyclonal Antibody
Rabbit polyclonal antibody targeting NPY, reactive with human, mouse, rat, and non-human primate. Suitable for WB and IHC applications. Lyophilized form with whole serum buffer, no preservative. Stable at -20°C for long-term storage.
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Applications
Western Blot (WB)
- Tested Dilution: 1:250–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 20–60 of mouse NPY conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in many other species including human, rat, zebrafish, and xenopus.
- Specificity: NPY.
Target Information
This gene encodes a neuropeptide widely expressed in the central nervous system, influencing physiological processes such as cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function.
The neuropeptide acts through G protein-coupled receptors to inhibit adenylyl cyclase, activate MAP kinase, regulate intracellular calcium levels, and activate potassium channels.
A polymorphism resulting in leucine 7 to proline substitution is associated with elevated cholesterol, higher alcohol consumption, and potential risk for metabolic and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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